A prospective observational study was performed in the period from Feb 2010 to Apr 2012. The study comprised 100 couples who underwent IUI cycles. All IUI cycles were preceded by ovarian induction with clomiphene citrate 100 mg daily for 5 days from third day of menstrual cycle, and HMG 150 IU daily for 3-4 days from eighth day of menstrual cycle. 10000 IU of HCG was given when at least one dominant follicle reached ≥ 18 mm (monitored by vaginal ultrasound). The IUI was performed at 36 hours after HCG injection. Main outcome measure: Clinical pregnancy. A total of 28 clinical pregnancies were obtained, for a pregnancy rate per cycle of 28%. The pregnancy rate per cycle was 28.6% for 2 clinical pregnancies (7 patients) when normal sperm morphology ≤ 4%, and was 31.8% for 14 clinical pregnancies (44 patients) when normal sperm morphology 5-14%, and was 23.3% for 10 clinical pregnancies (43 patients) when normal sperm morphology 15-30%, and was 33.3% for 2 clinical pregnancies (6 patients) when normal sperm morphology ≥ 30%.(p. value > 0.05). In conclusion, sperm morphology does not affect the outcome of IUI.