IMSI

Intracytoplasmic Morphology Selected Sperm Injection (IMSI)
In Assisted reproductive technology many factors are affecting the fertilization and embryo development potential, the DNA integrity of the spermatozoon being one of the major factors. To minimize the paternal contribution in IVF failure, sperm selection based on morphological and nuclear aspects showed a clear benefit of intracytoplasmic morphologically selected sperm injection (IMSI), with high magnification in clinical pregnancies outcome. IMSI is a method of spermatozoa selection based on high resolution microscopy which allows the enlargement (x 6000), thus a fine visualization of the head morphology of the spermatozoa. The evaluation of their degree of “vacuolization” allows a preselection of the spermatozoa before ICSI, so only the best sperm are injected.
Intracytoplasmic morphologically selected sperm injection (IMSI) is one of the newest, most advanced fertility techniques. A very high powered microscope in our laboratory magnifies sperm to around 6,000 times. We find one with a good shape, which indicates good genetic quality, and then inject it into the egg.
Research indicates this can reduce the use of sperm with DNA damage, which can reduce the miscarriage rate and increase the chance of a successful pregnancy.

Is IMSI for me?
IMSI may be recommended where there is a history of recurrent miscarriage, high abnormal formation of sperm or history of high sperm DNA fragmentation. It may also be recommended in cases of